The UCLA Diagnostic Molecular Pathology performs a wide range of diagnostic nucleic acid-based tests for hereditary disorders, cancer diagnosis and management, and other conditions. As one of the first facilities of its kind in the country, we pioneered applications of diagnostic DNA-based testing for a wide variety of genetic and neoplastic diseases, as well as DNA fingerprint analysis. In addition to its clinical service role, the laboratory has been very active in basic and applied clinical research.
The UCLA Cytogenetics laboratory is headed by three American Board of Medical Genetics certified Cytogeneticists, and staffed by 20 California-licensed Clinical Cytogeneticists Scientists (CLS). Our lab performs cytogenetic analysis for both our in-patient population, community based physicians and independently run pathology laboratories, which includes a high volume of hematological cases. State-of the art technologies are employed, including molecular cytogenetic techniques, such as standard and multicolored FISH, array comparative genomic hybridization for a wide range of clinical settings from prenatal and postnatal diagnosis to cancer.
Services:
Detection of cytogenetic abnormalities in leukemias, lymphomas and solid tumors by standard and molecular cytogenetics on fresh and archival tissue
Prenatal and postnatal diagnosis of microdeletion syndromes and numerical aberrations
Array comparative genomic hybridization for detection of copy number variants
Identification of mutations in cystic fibrosis, fragile X syndrome, familial breast/ovarian cancer (BRCA1/2 genes), hereditary thrombophilias, Huntington disease and other genetic disorders
Prenatal sex determination and Rh typing, and determination of paternity, twin zygosity and surgical specimen identity by DNA fingerprinting
Education:
Cytogenetics Fellowship
Molecular Pathology Fellowship
Resident training
Limited License Cytogenetics Technologist Training
Clinical and Translational Research:
Clinical Research Services
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Faculty & Staff:
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Wayne
Grody,
M.D., Ph.D.
Professor and Chief of Molecular Pathology
CHS
1P-249
(310) 825-5648
wgrody@mednet.ucla.edu
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Nagesh P.
Rao,
Ph.D., F.A.C.M.G.
Professor and Chief of Clinical and Molecular Cytogenetics
Rehab cntr
22-26
(310) 794-7851
nrao@mednet.ucla.edu
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Fabiola
Quintero,
M.D., F.A.C.M.G.
Assistant Professor and Associate Director of Clinical and Molecular Cytogenetics Laboratory
Rehab Bldg.
22-26
(310) 794-9783
fquintero@mednet.ucla.edu
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Kangmo
Lu,
M.D., Ph.D.
Assistant Professor and Assistant Director of Clinical and Molecular Cytogenetics Laboratory
Rehab Center, Rm 2-226
310-825-0153
kangmolu@mednet.ucla.edu
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Lori
Noravian,
Supervisor, Cytogenetics Lab
Rehab cntr
22-26
(310) 825-9030
LNoravian@mednet.ucla.edu
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Paul
Colonna,
Lab Manager, Molecular path and Cytogenetics
Brentwood Annex
Room 401
(310) 794-2759
pcolonna@mednet.ucla.edu
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